Elagolix 834153-87-6

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ElagolixCAS:834153-87-6 Endometriosis N'ime ụlọ      


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Ndị inyom na-eji ọgwụ a eme ihe iji nyere aka belata oke mgbu n'ihi ọnọdụ a na-akpọ endometriosis.
Enwere ike ịgwọ ọrịa: Endometriosis
Aha aha: Orilissa
Klas ọgwụ: Ndị na-emegide LHRH (GnRH).
Nnweta: Achọrọ ndenye ọgwụ
Ime ime: Zere iji n'oge ime ime
Lactation: kpọtụrụ dọkịta tupu iji

Elagolix bụ ihe na-ahụ maka ọnụ ọnụ, ọgbọ nke abụọ, nke na-abụghị peptide dabere, obere ngwongwo molecule na nhọrọ nke gonadotropin na-ahapụ homonụ (GnRH; LHRH) antagonist, nwere ike imepụta homonụ na-egbochi ọrụ.N'okpuru nchịkwa ọnụ, elagolix na-asọmpi GnRH maka njikọ nnabata ma na-egbochi GnRH nnabata n'ime pituitary gland.Nke a na-egbochi mmepụta nke hormone luteinizing (LH) na hormone na-akpali akpali (FSH).N'ime ụmụ nwoke, mgbochi nke nzuzo nzuzo LH na-egbochi ntọhapụ nke testosterone.N'ime ụmụ nwanyị, mgbochi FSH na LH na-egbochi mmepụta estrogen site na ovaries.Mgbochi nke mgbaàmà GnRH nwere ike ịgwọ ma ọ bụ gbochie mgbaàmà nke steeti ọrịa na-adabere na homonụ mmekọahụ.

Elagolix bụ onye na-emegide gonadotropin na-ewepụta ọnụ, nke na-ebelata mmepụta estrogen ma na-eji agwọ ụdị endometriosis na-egbu mgbu n'ime ụmụ nwanyị.A na-ejikọta ọgwụgwọ Elagolix na ọnụ ọgụgụ dị ala nke elu enzyme serum n'oge ọgwụgwọ ma enwebeghị njikọ na ihe gbasara mmerụ ahụ na-ahụ maka ụlọ ọgwụ.

E jirila Elagolix mee ule n'ịmụ sayensị bụ isi na ọgwụgwọ nke Endometriosis, Folliculogenesis, Uterine Fibroids, Ọbara Uterine Dị Egwu, na Ọbara Ọbara Dị Elu.Dị ka nke 24 July 2018, Otú ọ dị, US Food and Drug Administration (FDA) kwadoro AbbVie's elagolix n'okpuru aha aha Orilissa dị ka onye mbụ na nanị ọnụ gonadotropin na-ahapụ hormone (GnRH) antagonist mepụtara kpọmkwem maka ụmụ nwanyị nwere oke mgbu endometriosis.A chọpụtala na endometriosis bụ otu n'ime ọrịa gynecologic a na-ahụkarị na United States.Karịsịa, atụmatụ na-egosi na otu onye n'ime ụmụ nwanyị iri nke afọ ịmụ nwa na-emetụta endometriosis ma na-enweta mgbaàmà mgbu na-agwụ ike.Ọzọkwa, ụmụ nwanyị ndị ọnọdụ a na-emetụta nwere ike ịta ahụhụ ruo afọ isii ruo afọ iri ma gaa leta ọtụtụ ndị dọkịta tupu ha enweta nyocha nke ọma.N'ikpeazụ, dị ka Orilissa (elagolix) kwadoro site na FDA n'okpuru nyocha nke mbụ, nkwenye ọhụrụ a na-agba ọsọ na-enye ndị ọkachamara ahụike nhọrọ ọzọ bara uru maka ịgwọ mkpa nke ụmụ nwanyị na-emetụta endometriosis, dabere n'ụdị ha kpọmkwem na oke mgbu nke endometriosis. .

Ọdịdị chemical

dsfs

Asambodo

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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Usoro njikwa ogo mba ụwa dị elu etinyela ntọala siri ike maka ire ahịa.

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Nlekọta dị mma na-aga n'ihu na usoro ndụ nke ngwaahịa ahụ niile iji hụ na ịdịmma na mmetụta ọgwụgwọ.

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