Abrocitinib

Nkọwa dị mkpirikpi:

Aha API Ngosipụta Onye mmepụta ihe Ụbọchị Mmebi Ikikere (US)
Abrocitinib Atopic dermatitis Pfizer Febụwarị 11, 2034


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Nkọwa ngwaahịa

Abrocitinib bụ ọnụ, obere molecule, Janus kinase (JAK) 1 inhibitor na mmepe maka ọgwụgwọ ndị okenye na ndị nọ n'afọ iri na ụma nwere oke atopic dermatitis.

A na-enyocha Abrocitinib na nyocha ụlọ ọgwụ NCT03796676 (JAK1 Inhibitor With Medicated Topical Therapy in Adolescent with Atopic Dermatitis).

Pfizer na-emepụta Abrocitinib ugbu a maka ọgwụgwọ atopic dermatitis (eczema).Ọ bụ onye na-egbochi Janus kinase 1 (JAK1) otu ugboro kwa ụbọchị nyocha.

Atopic dermatitis (AD) bụ mgbagwoju anya, nke na-adịghị ala ala, ọrịa akpụkpọ ahụ na-egbuke egbuke nke e ji itching, oké itching, na eczematous ọnya na-emetụta ihe dịka 25% ụmụaka na 2% ruo 3% nke ndị okenye n'ụwa nile.Abrocitinib bụ onye na-emechi emechi nke Janus kinase-1 (JAK1) enzyme na-egbochi usoro mkpali.Ya mere, anyị bu n'obi iji nyochaa ịdị irè na nchekwa nke abrocitinib maka AD na-agafeghị oke na nke siri ike.

Abrocitinib na dose 100 mg ma ọ bụ 200 mg bụ ọgwụ dị irè, nke anabatara nke ọma na nke na-ekwe nkwa n'ịgwọ ndị ọrịa nwere oke atopic dermatitis.Otú ọ dị, nyocha ahụ kwadoro ịdị irè nke abrocitinib 200 mg karịa 100 mg, ma mmetụta ndị dị ka ọgbụgbọ na isi ọwụwa nwere ike ime karịa na 200 mg.

Asambodo

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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