Chlorothiazide
ndabere
Chlorothiazide bụ onye na-egbochi carbonic anhydrase ma nwee ike dị ntakịrị karịa acetazolamide.Egosiputara onyinye a iji gbochie reabsorption nke sodium na ion chloride.
Nkọwa
Chlorothiazide bụ ọgwụ diuretic na antihypertensive.(IC50=3.8 mM) Ebumnuche: Ndị ọzọ Chlorothiazide sodium (Diuril) bụ diuretic a na-eji n'ime ụlọ ọgwụ ma ọ bụ maka ojiji nkeonwe iji jikwaa oke mmiri nke jikọtara ya na nkụchi obi.A na-ejikwa ya dị ka antihypertensive.A na-ewerekarị ya n'ụdị pill, a na-aṅụkarị ya otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị.Na ntọala ICU, a na-enye chlorothiazide iji diurese onye ọrịa na mgbakwunye na furosemide (Lasix).Na-arụ ọrụ na usoro dị iche karịa furosemide, ma na-abanye n'ime ya dị ka nkwusioru eweghachiri eweghachi site na tube nasogastric (NG tube), ọgwụ abụọ ahụ na-eme ka ibe ha nwee ike.
Ọnwụnwa ụlọọgwụ
Nọmba NCT | Onye nkwado | Ọnọdụ | Ụbọchị mmalite | Usoro |
NCT03574857 | Mahadum Virginia | Obi ada ada|Obi ada ada site na mbelata nchụpụ nchụpụ|Obi ada ada|Ọrịa ọrịa obi | Ọnwa Isii 2018 | Agba 4 |
NCT02546583 | Mahadum Yale | National Heart, Lung, and Blood Institute (NHLBI) | Obi ọdịda | Ọgọst 2015 | Ọ metụtaghị |
NCT02606253 | Mahadum Vanderbilt | Mahadum Ahụike Mahadum Vanderbilt | Obi ọdịda | Febụwarị 2016 | Agba 4 |
NCT00004360 | National Center for Research Resources (NCRR) | Mahadum Northwwest | Office of Rare Diseases (ORD) | Ọrịa shuga Insipidus, Nephrogenic | Septemba 1995 |
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NCT00000484 | National Heart, Lung, and Blood Institute (NHLBI) | Ọrịa obi | Ọrịa obi | Eprel 1966 | Nkeji 3 |
Ọdịdị chemical
Atụmatụ18Ọrụ nlebanya na-agbanwe agbanwe nke akwadoro4, na6A na-akwado ọrụ ngo.
Usoro njikwa ogo mba ụwa dị elu etinyela ntọala siri ike maka ire ahịa.
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Ndị otu Regulatory Affairs ndị ọkachamara na-akwado ịdịmma chọrọ n'oge ngwa na ndebanye aha.