Crisaborole
Crisaborole bụ otu n'ime klas nke benzoxaboroles nke bụ 5-hydroxy-1,3-dihydro-2,1-benzoxaborole nke phenolic.hydrogene jiriwo otu 4-cyanophenyl dochie ya. A phosphodiesterase 4 inhibitor nke a na-eji maka ọgwụgwọ atopic dermatitis dị nro ma na-agafeghị oke na ụmụaka na ndị okenye. Ọ nwere ọrụ dị ka phosphodiesterase IV inhibitor, anantipsoriaticna ọgwụ mgbochi mkpali na-abụghị steroidal. Ọ bụ benzoxaborole, ether aromatic na nitrile.
Crisaborole bụ akwụkwọ akụkọoxaboroleFDA kwadoro na Disemba 14, 2016 dị ka Eucrisa, ọgwụgwọ n'elu maka dermatitis dị nro na nke na-agafeghị oke. Onye na-abụghị steroidal a na-arụ ọrụ nke ọma n'ịkwalite oke ọrịa, na-ebelata ihe ize ndụ nke ibute ọrịa na ibelata akara na mgbaàmà na ndị ọrịa 2 afọ na karịa. Ọ na-ebelata mbufụt mpaghara na akpụkpọ ahụ ma gbochie ọrịa ahụ na-emewanyewanye nke ọma na profaịlụ nchekwa dị mma. Ọdịdị ya nwere aboronatom, nke na-eme ka ntinye anụ ahụ dị mfe ma jikọta ya na etiti bimetal nke phosphodiesterase 4 enzyme. A na-emepe ya ugbu a dị ka ọgwụgwọ n'elu nke psoriasis.
Crisaborole bụ ihe mgbochi phosphodiesterase 4. Usoro nke crisaborole na-eme ihe dị ka ihe mgbochi phosphodiesterase 4.





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