Paxlovid bụ ọgwụ nyocha nke a na-eji agwọ COVID-19 dị nro na nke na-adịghị ala ala n'ime ndị okenye na ụmụaka [afọ 12 na okenye na-eru opekata mpe kilogram 88 (kg 40)] nwere nsonaazụ dị mma nke nnwale nje SARS-CoV-2. na ndị nọ n'ihe egwu dị elu maka ịga n'ihu ruo ajọ COVID-19, gụnyere ụlọ ọgwụ ma ọ bụ ọnwụ. A na-enyocha Paxlovid n'ihi na a ka na-amụ ya. Enwere obere ozi gbasara nchekwa na ịdị irè nke iji Paxlovid na-agwọ ndị nwere COVID-19 dị nwayọọ ruo na-agafeghị oke.
FDA enyela ikike iji ihe mberede Paxlovid mee ihe maka ọgwụgwọ COVID-19 dị nro na-agafeghị oke n'ime ndị okenye na ụmụaka [afọ 12 na karịa na-eru opekata mpe 88 pound (40 n'arọ)] na nnwale dị mma maka nje ahụ. na-ebute COVID-19, yana ndị nọ n'ihe ize ndụ dị ukwuu maka ịga n'ihu ruo ajọ COVID-19, gụnyere ụlọ ọgwụ ma ọ bụ ọnwụ, n'okpuru EUA.

Paxlovid abụghị ọgwụ FDA kwadoro na United States. Gwa onye na-ahụ maka ahụike gị gbasara nhọrọ gị ma ọ bụ ọ bụrụ na ị nwere ajụjụ ọ bụla. Ọ bụ nhọrọ gị ka ị were Paxlovid.

Paxlovid nwere ọgwụ abụọ: nirmatrelvir na ritonavir.

Nirmatrelvir [PF-07321332] bụ onye na-egbochi SARS-CoV-2 bụ isi protease (Mpro) (nke a makwaara dị ka SARS-CoV2 3CL protease inhibitor) nke na-arụ ọrụ site na igbochi mmegharị nje na mmalite nke ọrịa ahụ iji gbochie ọganihu na nnukwu COVID- 19.

A na-ejikọta Ritonavir na nirmatrelvir iji nyere aka belata metabolism ya ka ọ nọgide na-arụsi ọrụ ike n'ime ahụ ruo ogologo oge na ntinye dị elu iji nyere aka ịlụso nje ọgụ ọgụ.