Calcium Pitavastatin
| 匹伐他汀钙 | Pitavastatin | 147526-32-7 | N'ime ụlọ |
| PI-5 | 3800-06-4 | N'ime ụlọ | |
| PI-6 | 145516-11-4 | N'ime ụlọ | |
| PI-7 | 121660-11-5 | N'ime ụlọ |
Nkọwa
Calcium Pitavastatin (NK-104 hemicalcium) bụ ihe na-egbochi hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor.Calcium Pitavastatin (NK-104 hemicalcium) na-egbochi njikọ cholesterol sitere na acetic acid yana IC50 nke 5.8 nM na sel HepG2.Calcium Pitavastatin bụ ihe na-anabata nnabata nke lipoprotein-cholesterol (LDL-C) nke hepatocyte dị ala.Ọrụ mgbochi ọrịa kansa.
ndabere
Calcium Pitavastatin bụ ihe na-egbochi enzyme HMGCR (HMG-CoA reductase) na-ebute mbelata njikọ LDL cholesterol.Nnyocha ọzọ na-egosi na pitavastatin nwere ike igbochi mmepụta oxygen na mkpụrụ ndụ endothelial site na igbochi NADPH oxidase.Na mgbakwunye, pitavastatin na-ebelata okwu eNOS mRNA ebe ọ na-abawanye nzaghachi dabere na NO nke acetylcholine na calcium ionophore, A23187 kpaliri.Ọzọkwa, pitavastatin na-egbochi njikwa njikwa nke ọwa potassium na-arụ ọrụ calcium site na ibelata ọkwa cholesterol na sel.
Nchekwa
4°C, chebe pụọ na ìhè
* Na ihe mgbaze: -80°C, ọnwa 6;-20°C, ọnwa 1 (chebe ọkụ)
Ọdịdị chemical
Data bayoloji emetụtara
Atụmatụ18Ọrụ nlebanya na-agbanwe agbanwe nke akwadoro4, na6A na-akwado ọrụ ngo.
Usoro njikwa ogo mba ụwa dị elu etinyela ntọala siri ike maka ire ahịa.
Nlekọta dị mma na-aga n'ihu na usoro ndụ nke ngwaahịa ahụ niile iji hụ na ịdịmma na mmetụta ọgwụgwọ.
Ndị otu Regulatory Affairs ndị ọkachamara na-akwado ịdịmma chọrọ n'oge ngwa na ndebanye aha.
Ahịrị nkwakọ ngwaahịa Korea Countec
Taiwan CVC ahịrị nkwakọ ngwaahịa
Line CAM Board Ịtali
Igwe na-akpakọrịta Fette German
Ihe nchọpụta mbadamba ihe ngosi nke Japan
Ụlọ njikwa DCS
