Calcium nke rosuvastatin
| 瑞舒伐他汀钙 | Calcium nke rosuvastatin | 147098-20-2 | N'ime ụlọ/CEP |
| kristal (RSM) | 147118-40-9 | N'ime ụlọ | |
| RSM( Crude) | 147118-40-9 | N'ime ụlọ | |
| RSP | - | N'ime ụlọ | |
| RS-8 | 147118-36-3 | N'ime ụlọ | |
| RS-8-1 | 147118-37-4 | N'ime ụlọ | |
| TP-8 | 131466-61-0 | N'ime ụlọ | |
| TP-11 | 147118-35-2 | N'ime ụlọ | |
| TP-13 | 147118-39-6 | N'ime ụlọ | |
| RS-10 | 289042-12-2 | N'ime ụlọ | |
| RS-11 | 355806-00-7 | N'ime ụlọ |
Nkọwa
A na-akpọ Calcium Rosuvastatin (BANM, JAN, USAN) dị ka Rosuvastatin na US.na ihe mgbochi HMG-CoA reductase inhibitor nwere IC50 nke 11 nM[1].Calcium Rosuvastatin na-egbochi mkpụrụ ndụ ihe nketa ether-a-go-go mmadụ (hERG) dị ugbu a yana IC50 nke 195 nM, na-egbu oge nkwughachi obi, wee si otú a mee ogologo oge ọrụ nwere ike ime (APDs) wee mezie nkeji oge QT (QTc).Calcium Rosuvastatin na-ebelata ngosipụta nke hERG tozuru oke yana mmekọrịta nke protein ujo 70 (Hsp70) na protein hERG.Calcium Rosuvastatin na-arụ ọrụ nke ọma n'ibelata lipoprotein dị obere (LDL), triglycerides na protein C-reactive [3].
Ozi ndị ọzọ gbasara mgbakọ n'ịkpọ aha ọgwụ: International Nonproprietary Names.
Ọkwa dị mkpa: Drugs.com nchekwa data mba ụwa dị na ntọhapụ BETA.Nke a pụtara na ọ ka na-etolite ma nwee ike ịnwe ezighi ezi.Ebubeghi ya ka ọ nọchiri anya nka na ikpe nke dibịa gị, onye na-ere ọgwụ ma ọ bụ ọkachamara ahụike ọzọ.E kwesịghị ịkọwa ya iji gosi na iji ọgwụ ọ bụla na obodo ọ bụla dị mma, dabara ma ọ bụ dị irè maka gị.Kpọtụrụ ọkachamara ahụike gị tupu ị were ọgwụ ọ bụla.
Na US, Rosuvastatin (rosuvastatin systemic) bụ onye so na klas ọgwụ statins ma na-eji agwọ Atherosclerosis, Cholesterol dị elu, Cholesterol dị elu - Ezinụlọ Heterozygous, Cholesterol dị elu - Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Ụdị IIa - elu LDL, Hyperlipoproteinemia Type IIa - elu LDL, hyperlipoproteinemia. IIb - LDL VLDL dị elu, Hyperlipoproteinemia Ụdị III - Beta-VLDL IDL dị elu, Hyperlipoproteinemia Ụdị IV - VLDL dị elu, Hypertriglyceridemia na Mgbochi Ọrịa obi.
ndabere
Nhọrọ, onye na-egbochi asọmpi nke HMG-CoA reductase, nke ahụ bụkwa antilipemic.
Nchekwa
| Ntụ ntụ | -20°C | Afọ 3 |
| 4°C | afọ 2 | |
| Na ihe mgbaze | -80 Celsius | Ọnwa isii |
| -20°C | 1 ọnwa |
Ọdịdị chemical
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