Nkọwa

A na-akpọ Calcium Rosuvastatin (BANM, JAN, USAN) dị ka Rosuvastatin na US. yana ihe mgbochi HMG-CoA reductase inhibitor nwere IC50 nke 11 nM[1]. Calcium Rosuvastatin na-egbochi ike mmadụ ether-a-go-go gene (hERG) dị ugbu a na IC50 nke 195 nM, na-egbu oge nkwụghachi obi, wee si otú a mee ogologo oge ọrụ nwere ike ime (APDs) wee mezie nkeji oge QT (QTc). Calcium Rosuvastatin na-ebelata ngosipụta nke hERG tozuru oke yana mmekọrịta nke protein ujo 70 (Hsp70) na protein hERG. Calcium Rosuvastatin na-arụ ọrụ nke ọma n'ibelata lipoprotein dị obere (LDL), triglycerides na protein C-reactive [3].

Ozi ndị ọzọ gbasara mgbakọ n'ịkpọ aha ọgwụ: International Nonproprietary Names.

Ọkwa dị mkpa: nchekwa data mba ụwa Drugs.com dị na ntọhapụ BETA. Nke a pụtara na ọ ka na-etolite ma nwee ike ịnwe ezighi ezi. Ebubeghi ya ka ọ nọchiri anya nka na mkpebi nke dibịa gị, onye na-ere ọgwụ ma ọ bụ ọkachamara ahụike ọzọ. E kwesịghị ịkọwa ya iji gosi na iji ọgwụ ọ bụla na obodo ọ bụla dị mma, dabara ma ọ bụ dị irè maka gị. Kpọtụrụ ọkachamara ahụike gị tupu ị were ọgwụ ọ bụla.

Na US, Rosuvastatin (rosuvastatin systemic) bụ onye so na klas ọgwụ statins ma na-eji agwọ Atherosclerosis, Cholesterol dị elu, Cholesterol dị elu - Ezinụlọ Heterozygous, Cholesterol dị elu - Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa - elu LDL, ụdị hyperlipoproteinemia. IIb - LDL VLDL dị elu, Hyperlipoproteinemia Ụdị III - Beta-VLDL IDL dị elu, Hyperlipoproteinemia Ụdị IV - VLDL dị elu, Hypertriglyceridemia na Mgbochi Ọrịa Obi.

ndabere

Nhọrọ, onye na-egbochi asọmpi nke HMG-CoA reductase, nke ahụ bụkwa antilipemic.

Nchekwa

Ọdịdị chemical