Ndị na-emepụta China Captopril na ndị na-ebubata

Captopril

Nkọwa dị mkpirikpi:

Aha API	Ngosipụta	Nkọwapụta	US DMF	EU DMF	CEP
Captopril	Ọbara mgbali elu	USP/EP	√	√

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Captopril (SQ-14534) bụ onye na-egbochi ihe mgbochi nke angiotensin na-agbanwe enzyme (ACE).

Na Vitro

Captopril (SQ-14534) egosila na ọ nwere ụdị ọrịa na-anwụ anwụ na uru nke diuretics na beta-blockers na ndị ọrịa nwere ọbara mgbali elu. Captopril (SQ-14534) egosila na ọ na-egbu oge na-aga n'ihu nke nephropathy na-arịa ọrịa shuga, yana enalapril na lisinopril na-egbochi mmepe nke nephropathy na ndị ọrịa normoalbuminuric nwere ọrịa shuga[1]. Oke nhata nke steeti cis na trans nke Captopril (SQ-14534) dị na ngwọta yana na enzyme na-ahọrọ naanị ọnọdụ trans nke inhibitor nke na-enye mmekọ ụkpụrụ ụlọ na stereoelectronic ya na oghere na-ejikọta mkpụrụ ya [2].

MCE akwadobeghị izi ezi nke ụzọ ndị a. Ha bụ naanị maka ntụnye aka.

Ọnwụnwa ụlọọgwụ

Nọmba NCT	Onye nkwado	Ọnọdụ	Ụbọchị mmalite	Usoro
NCT03179163	Mahadum Penn State \| National Heart, Lung, and Blood Institute (NHLBI)	Ọbara mgbali elu, dị mkpa	Ọnwa Asaa 20, 2016	Agba 1 \| Nkeji 2
NCT03660293	Mahadum Tanta	Ọrịa shuga mellitus, ụdị 1	Eprel 1, 2017	Ọ metụtaghị
NCT03147092	Centro Neurológico de Pesquisa na Reabiitação, Brazil	Ọbara mgbali elu\|Ọbara mgbali	Febụwarị 1, 2018	Agba mbụ 1
NCT00252317	Rigshospitalet, Denmark	Aortic stenosis	Nọvemba 2005	Agba 4
NCT02217852	West China Hospital	Ọbara mgbali elu	Ọgọst 2014	Agba 4
NCT01626469	Ụlọ ọgwụ Brigham na Women's Hospital	Ụdị ọrịa shuga mellitus nke 2	Mee 2012	Agba 1 \| Nkeji 2
NCT00391846	AstraZeneca	Ọdịda Obi \| Ọgba aghara ventricular, aka ekpe	Ọktoba 2006	Agba 4
NCT00240656	Hebei Medical University	Ọbara mgbali elu, Pulmonary	Ọktoba 2005	Agba 1
NCT00086723	Mahadum Northwwest \| National Cancer Institute (NCI)	Tumor siri ike nke okenye anaghị akọwapụta ya, Pụrụ iche Protocol	Julaị 2003	Agba 1 \| Nkeji 2
NCT00663949	Mahadum Shiraz nke Science Medical	Ọrịa mamịrị nephropathy	Febụwarị 2006	Agba 2 \| Nkeji 3
NCT01437371	Ụlọ ọgwụ University, Clermont-Ferrand \| Onye ọrụ \| LivaNova	Obi ọdịda	Ọgọst 2011	Nkeji 3
NCT04288700	Mahadum Ain Shams	Hemangioma nwa ọhụrụ	Ọktoba 1, 2019	Agba 4
NCT00223717	Mahadum Vanderbilt \| Mahadum Ahụike Mahadum Vanderbilt	Ọbara mgbali elu	Jenụwarị 2001	Agba 1
NCT02770378	Mahadum Ulm \| Usoro ọgwụgwọ ọrịa kansa a pụrụ ịdabere na ya	Glioblastoma	Nọvemba 2016	Agba 1 \| Nkeji 2
NCT01761916	Instituto Materno Infantil Prof. Fernando Figueira	Preeclampsia	Jenụwarị 2013	Agba 4
NCT01545479	Instituto de Cardiologia na Rio Grande do Sul	Ọrịa gbasara akụrụ	Jenụwarị 2010	Agba 4
NCT00935805	Hospital de Clinicas de Porto Alegre\|Conselho Nacional de Desenvolvimento Científico e Tecnológico\|Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil	Ọrịa shuga mellitus \| Ọbara mgbali elu	Julaị 2006
NCT00742040	Ụlọ ọgwụ maka ụmụaka na-arịa ọrịa	Ọrịa obi	Ọgọst 2008	Agba 2
NCT03613506	Mahadum Wuhan	Mmetụta Radiotherapy \| Ịnweta Captopril	Ọktoba 25, 2018	Agba 2
NCT00004230	Mahadum Northwwest \| National Cancer Institute (NCI)	Ọrịa cancer	Ọktoba 1999	Nkeji 3
NCT00660309	Novartis	Ụdị ọrịa shuga mellitus nke 2	Eprel 2008	Agba 4
NCT00292162	NHS Greater Glasgow na Clyde	Ọdịda Obi Na-adịghị Ala Ala\|Atrial Fibrillation	Jenụwarị 2007	Ọ metụtaghị
NCT01271478	Coordinación de Investigación en Salud, Mexico	Mbufụt\|Ọrịa gbasara gbasara akwara ozi	Ọgọst 2009	Agba 4
NCT04193137	Mahadum Medical Chongqing	Aldosteronism nke mbụ	Nọvemba 30, 2019
NCT00155064	Ụlọ ọgwụ Mahadum National Taiwan	Hyperaldosteronism	Julaị 2002	Agba 4
NCT01292694	Mahadum Vanderbilt \| Mahadum Ahụike Mahadum Vanderbilt	Ọbara mgbali elu\|Ọdịghị arụrụ arụrụala \| Ọtụtụ Sistemụ Atrophy	Maachị 2011	Agba 1
NCT00917345	Ụlọ ọgwụ Mahadum National Taiwan \| Novartis	Aldosteronism nke mbụ	Jenụwarị 2008
NCT00077064	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)\|NRG Oncology	Ọrịa cancer akpa ume \| Nsogbu akpa ume \| Radiation Fibrosis	June 2003	Agba 2